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Cells , 14 (14), 1096

Bttger R, et al

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-oxidation Applications in Scientific Research Mitochondrial Bioenergetics Measurement of fatty acid -oxidation ATP production from lipids Function of the respiratory chain Cellular respirometry Enzymatic Research Kinetics of CPT-1A, CPT-1B, CPT-2 Substrate specificity Inhibition by malonyl-CoA CACT characteristics Lipid metabolism Transport of fatty acids Acylcarnitine profile Ketogenesis Interaction with glucose metabolism Comparative Research L-carnitine vs acetyl-L-carnitine Differences between CPT isoforms Effects of carnitine deficiency (in vitro) Summary L-Carnitine is an endogenous compound that plays a key role in the transport of long-chain fatty acids to the mitochondria

2 Department of Psychiatry, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA