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Ionomycin significantly increased PS exposure in all conditions when compared to the DMSO control: Ringer (2.4% to 24%, p =0.0004), Ringer+Albumax (0.72% to 22%, p =0.0005), iRPMI (0.63% to 23%, p =0.0003) and iRPMI+Albumax (0.43% to 15%, p =0.0329)

Mice were randomly assigned to one of two groups: a vehicle control group (V-CNT) and a B12-supplemented group (SUPP)

This behavior was similar to hexokinase shunt to increase ADP when ATP synthesis was urgent required [47] Aceyl-L-carnitine be metabolized rapidly when it was injected IV because it was transported to mitochondria directly and acetyl moiety was released into mitochondria by acetyltransferase [38]

doi: 10.1007/978-3-030-38881-2_4 62 EzakiB.JayaramK.HigashiA.TakahashiK