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mTOR, as a key effector of autophagy, inhibits the activation of ULK1, which is regulated by multiple pathways [175]

( D ) mCherry low sorted lung metastatic cell lines stably expressing ipCW, ipCW- Gstt1 wild-type and ipCW- Gstt1 R234G were treated with doxycycline for 5 days and subsequently subjected to soft agar growth assay

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Cellular proliferation can be assayed using art recognized techniques which measure rate of cell division, the fraction of cells within a cell population undergoing cell division, and/or rate of cell loss from a cell population due to terminal differentiation or cell death (e.g., using a cell titer glow assay or thymidine incorporation)

However, patient satisfaction scores were significantly higher in the flutamide group (Adalatkhah and Sadeghi-Bazargani, 2015)