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In addition, lycopene can enter the central nervous system through the blood-brain barrier, lycopene dissolved in olive oil and lycopene-loaded microemulsion improve oral bioavailability and have good brain targeting ability (113) (see Table 6 )

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2019;27(2):491-501.e6

Florenzano P, Jimenez M, Ferreira CR, Nesterova G, Roberts MS, Tella SH, Fernandez de Castro L, Gafni RI, Wolf M, Juppner H, Gales B, Wesseling-Perry K, Markovich D, Gahl WA, Salusky IB, Collins MT (2020) Nephropathic cystinosis: a distinct form of CKD-mineral and bone disorder that provides novel insights into the regulation of FGF23