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Description

As a result, the systemic exposure to the unconjugated form is typically low and highly sensitive to individual differences in metabolic enzyme activity (e.g., UGTs and SULTs), leading to marked inter-individual variability

As shown in Figure 7 , in mock- and GSTP1 -transfected HepG2 cells dose- and time- dependent up-regulations of CHOP-GFP signal were detected following treatment with AQ-QI or DEAQ-QI

doi: 10.1074/jbc.M609521200

DOI: 10.1016/j.intimp.2023.110165

The observed increase in MG concentrations in the context of acute and chronic kidney injury suggests a close association between MG accumulation and renal impairment