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These in vitro mechanisms were recapitulated ex vivo, as observed by the strong correlations of ex vivo 15LO1 protein with intracellular GSH ( r = 0.68, P = 0.005) and GSH:GSSG ( r = 0.62, P = 0.014) in freshly brushed HAECs (Figure 3F)

Next, we used qPCR to validate the expression levels of two genes, catalase (CAT) and superoxide dismutase (SOD) (Fig

The hypothesis for this study is that one of the mechanisms by which Pro improves preimplantation embryo development is by increasing the concentration of GSH and reducing oxidative stress

Glutathione or a salt thereof in the form of spherical particles can be advantageously formulated in tablet form by direct compression together with suitable excipients