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b : A shared group estimation plot comparing the effect of metformin on the volume of individual adenoma organoids generated from Apc fl/fl mice (n = 3) on days 1 and 5 post seeding

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At P21, hanging wire was performed in which the mouse was allowed to grasp a wire 30 cm off the ground and time for its latency to fall

Most common possible reasons for incorrect predictions were post-hoc identified as artifacts (n = 10), stenosis of vessels (n = 2) and old infarcts (n = 2)

Thiamine absorption in the jejunum involves both passive diffusion and active transport, with thiamine being converted into thiamine pyrophosphate (TPP)