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Pharmacogenetics 14 , 118

& Falath, W

Probiotics can influence the immune system by promoting the production of anti-inflammatory cytokines, such as IL-10 and transforming growth factor-beta (TGF- ), while simultaneously reducing pro-inflammatory cytokines like TNF- and IL-6 (108)

Both the cascade of secondary effects and the long-term effects are consequences of the primary insult and are susceptible to interventions to improve resilience or to treat TBI