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It also exhibits neuroprotective properties, safeguarding brain cells from damage

Mechanistic analysis supported piperines therapeutic potential against oral cancer in vivo , revealing that it induced autophagy and apoptosis by inhibiting the PI3K/Akt/mTOR pathway ( 4.6.3 Ferroptosis Iron-dependent lipid peroxidation and the catastrophic disruption of redox homeostasis are hallmarks of ferroptosis, a regulated, non-apoptotic form of cell death (96)

doi: 10.3390/cells12030377 47 FaintrenieGGlonA

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The first one, a targeted approach, consisted in searching genes from families already described in the literature as implicated in the pathway