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Stability Stability of the high- and low-concentration PC was evaluated under two conditions: 5-repeated cycles of freeze (at -80 for minimum 12 h) and thaw (at room temperature for minimum 2 h), and long-term freeze at 80 for 12 weeks

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The comparison shows that concentration selection depends on three primary factors: subject body weight (smaller subjects require smaller volumes), target dose range (higher doses favor higher concentrations to avoid excessive injection volumes), and measurement precision (volumes below 0.05ml approach the reliability limit of standard 1ml insulin syringes even with 0.01ml graduations)

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