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doi: 10.1126/SCIENCE.AAR3318 239 ThomasC.GioielloA.NoriegaL.StrehleA.OuryJ.RizzoG.et al (2009)

however, under pathological conditions such as inflammatory bowel disease or ACM, certain species may overgrow, leading to dysbiosis (131)

Additionally, this Ca 2+ leak enhanced spontaneous Ca 2+ spark and Ca 2+ wave propensity, which was linked to LCAC-mediated in vivo premature ventricular complexes