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Aluminum (Al), cadmium (Cd), arsenic (As), mercury (Hg), lead (Pb), and chromium (Cr) and their roles in the development of gastrointestinal, pulmonary, kidney, reproductive, neurodegenerative (Alzheimers and Parkinsons diseases), cardiovascular, and cancer (e.g

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This finding can be explained by our structure, because in the presence of a disulphide between Cys73 hTrx1 and Cys73 hTrx1 , the hTrx1 residues 73 hTrx1 to 75 hTrx1 , which are involved in binding of hTrx1 to hTrxR1 (see above), are not available for hTrxR1hTrx1 complex formation (Fig

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MB is redox-active, undergoing reversible conversion between its oxidized (blue) and reduced (colorless leucomethylene blue) states