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96 MorrisD.KhurasanyM.NguyenT.KimJ.GuilfordF.MehtaR.et al (2013)

Excessive activation of autophagy may lead to renal tubular atrophy and fibrosis in some cases, but it can also exert anti-fibrotic effects by degrading excess collagen (Zhang et al., 2024)

As a result, it generally remains active longer than native IGF-1 under comparable conditions

Still, randomized trials and case reports sometimes list headache among reported side effects

Results: Out of the 1507 analyzed lipid species, we identified 8 significant lipid molecules associated with advanced fibrosis (F3-4) as compared to no or early-stage fibrosis (F0-2)