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This review examines the interconnections between circadian rhythms in kidney and eye health, focusing on shared pathological pathways including oxidative stress, inflammation, and fibrosis

Extracts were processed exactly as described in Cellular metabolomics analysis, including homogenization, protein precipitation, sonication, vacuum concentration, and HILIC reconstitution

The breakdown of GSH (and also of its oxidized form, GSSG) is catalyzed by -glutamyl transpeptidase, which catalyzes the transfer of the gamma-glutamyl moiety to acceptors such as SH-containing amino acids, certain dipeptides, and GSH itself (Reaction 3)