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Description

PMID 29061763

Pathogenesis of IgA nephropathy: current understanding and implications for development of disease-specific treatment

Studies in mice demonstrated that a short course of MOTS-c treatment completely reversed age-related insulin resistance in old muscles after one week of MOTS-c administration, older mices muscles responded to insulin as effectively as those of much younger mice

El-Hajjar L, Hindieh J, Andraos R, El-Sabban M, Daher J

The peptide suppresses pro-inflammatory cytokines including TNF-, IL-6, and TGF-, which are key drivers of chronic low-grade inflammation (inflammaging) in older skin