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In the context of Long COVID, where chronic neuroinflammation is a primary driver of cognitive dysfunction, the ability to epigenetically turn off inflammatory genes is a massive therapeutic advantage

These effects are typically mild to moderate, dose-dependent, and tend to diminish with continued use and proper dose escalation

J.LinT.-J.ZhengL.CoreasR.et al

Some of us might need much more than 2.4mcg to feel well or correct any deficiency although it would probably be pointed out to me that even taking just 1mg of tablet will mean that the patient will be getting four times the amount he or she needs to make healthy red blood cells

And compared to vaccines in the past, these are probably some of the most scrutinized vaccines we've ever had