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However, chronic stress induced pyknotic, degenerating pyramidal cells, along with vacuolization surrounding the degenerated cells in the PFC

4.3 Marine Microorganisms MacFarlane et al

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Acute exposure to gold nanoparticles aggravates lipopolysaccharide-induced liver injury by amplifying apoptosis via ROS-mediated macrophage-hepatocyte crosstalk

We therefore functionalized CCW16 as a POI recruitment ligand and designed a series of PROTACs, where CCW16 was linked to VHL032- and 4-hydroxy thalidomide-derived-E3 ligands, recruiting the E3 ligases VHL and CRBN, respectively