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Note: vitamin D supplementation dosage should be based on 25-hydroxyvitamin D blood levels

Abbreviations CKD chronic kidney disease CMAH cytidine monophospho- N -acetylneuraminic acid hydroxylase CVD cardiovascular disease FMO3 flavin monooxygenase 3 GM3 monosialodihexosylganglioside HCAs heterocyclic amines Neu5Ac N -acetylneuraminic acid Neu5Gc N -glycolylneuraminic acid NOCs N-nitroso compounds PAHs polycyclic aromatic hydrocarbons TGF- transforming growth factor beta TMA trimethylamine TMAO trimethylamineN-oxide WHO-IARC World Health Organization-International Agency for Research on Cancer Footnotes Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication

Cell studies suggest that it can help maintain healthy neuron growth

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Age-related health conditions and oxidative stress can also increase the bodys demands for L-carnitine