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MicroRNAs as potential diagnostic biomarkers for bipolar disorder

Both authors read and approved the submitted version

Mitesh Joshi, NMIMS Sunandan Divatia School of Science for providing help with figure artwork

Given the anatomical reality that the brainstem comprises many densely-packed but functionally-heterogeneous nuclei, any small errors in spatial registration caused by failure to use brainstem-specific registration are highly likely to lead to decreased sensitivity in signal and type 2 errors ( Furthermore, the brainstem is especially prone to physiologically-driven movement artifact given that it pulses with every heartbeat [e.g., ( A large majority of neuroimaging studies in ME/CFS have not used brainstem-specific spatial co-registration, normalization, or physiologically-derived movement artifact regression techniques

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