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Although the androgen signaling pathway can be disrupted in different ways, from reduced testosterone synthesis to blocking of AR binding, we refer to compounds that interfere with any step of the androgen signaling pathway as anti-androgenic compounds

Cham, 2946

These opposing roles of distinct PRDX isoforms suggest that PRDXs function not simply as antioxidant enzymes but as context-dependent determinants of ferroptosis sensitivity

Libraries were prepared using the Universal Plus mRNA-seq protocol (Tecan) according to the manufacturers protocol