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While normal cells preserve membrane localization of EAATs, their mislocalization in malignant cells together with up-regulation of xCT lead to aberrant handling of glutamate that induces high levels of glutamate in the extracellular space, as seen in gliomas (192) and in breast cancer, where endocrine therapy-resistant cells promote autophagy and glutamate import via EAAT2 (60, 193)

Efficacy and safety of Zicuiyin decoction on diabetic kidney disease: a multicenter, randomized controlled trial

Inflammation-induced iron transport and metabolism by brain microglia

Avoid rubbing the injection site and let warm medication reach room temperature before use

It can help a formula feel more refined when the main goals are smoother-looking texture and a less creased surface appearance