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Description

CRISPRi-Ready ioGlutamatergic Neurons demonstrate gene expression of neuronal-specific and glutamatergic-specific markers following deterministic cell programming Gene expression analysis at day 11 demonstrates that CRISPRi-Ready ioGlutamatergic Neurons (CRISPRi) and wild-type ioGlutamatergic Neurons (WT) lack the expression of pluripotency markers (OCT4 and NANOG), while robustly expressing pan-neuronal (TUBB3 and SYP) and glutamatergic-specific (VGLUT1 and VGLUT2) markers, as well as the glutamate receptor GRIA4