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doi: 10.3945/an.114.005835 72 DuanH.YuL.TianF.ZhaiQ.FanL.ChenW

For inducible transcriptional downregulation, cells were infected with the hu-GCLC or hu-CAT Tet-inducible lentiviral shRNA system (Dharmacon SMARTvector, Horizon, Cambridge, UK)

ZhangXLvSZhangWJiaQWangLDingYet al

71 Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) were firstly identified as key enzymes which promote PUFAs into PLs for forming PL-PUFAs and induce ferroptosis

Transgenic animals engineered to overexpress -Syn are utilized to explore the role of this protein in the degeneration of dopaminergic cells (Prymaczok, et al