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In the proposed rule and this final rule, we seek to make readers aware that efforts to update the SAFER Guides are currently underway

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It should be noted, however, that because AF is often asymptomatic, and until recently was rarely screened for, many/most of these studies are actually post hoc [30,31,32,33], i.e., they study the incidence of AF in people who have had cardiovascular events rather than the other way round (i.e., for our present purposes, the incidence of heart attacks and strokes in those with known, pre-existing AF)