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Giglio P, Gagliardi M, Tumino N, Antunes F, Smaili S, Cotella D, et al

Table 4 Toxic metal contaminants and associated risks in edible mushrooms

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In the GPX4-dependent ferroptosis pathway, the CNC transcription factor NFE2L2/NRF2 plays a crucial regulatory role by activating GPX4 through SLC7A11 to suppress ferroptosis [136]