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IGF-1 is a highly anabolic peptide hormone responsible for: Muscle cell proliferation and repair Tendon and ligament regeneration Bone growth Glucose uptake in muscle cells Increased satellite cell activation Oral administration of MK-677 raised serum IGF-1 levels by over 60% in healthy adults without altering cortisol, insulin, or gonadotropin concentrations. Chapman et al., Clinical Pharmacology & Therapeutics This rise in IGF-1 is what leads to muscle growth, improved recovery, and increased physical resilience over time

With a half-life under 2 hours, its GH-boosting effect persists for 2-3 hours following injection

Your body naturally releases its largest pulse of growth hormone during the first cycle of deep sleep

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