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A recent study reported that the exogenous administration of BHB post-ischemia downregulates both the PERK and the IRE1 branches of the UPR (Montiel et al., 2023)

doi: 10.1016/j.imlet.2017.05.010

The study also indicated that the signal-regulating activity of hydrogen may be a key mechanism underlying its protective effect against PD

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Important: Current scientific evidence for routine IV therapy use in healthy, well-nourished athletes remains limited