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Similarly, the inflammasome pathway was activated by prolonged iron overload in iRPE cells, as highlighted by increased NLRP3 protein levels ( p = 0.0012 compared with those in control cells

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Leaf flavonoids (kaempferol and rutin) attenuate hydrogen peroxide-induced apoptosis in human umbilical vein endothelial cells and decrease the production of reactive oxygen species and malondialdehyde (MDA) production

In this regard, in healthy subjects, having a mixed meal, a combination of protein, carbohydrates, and fat, followed by a higher energy expenditure, prolonged the rate of gastric emptying and resulted in lower glycemia compared with a meal of carbohydrates alone [14]