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To quantify the transcript level, a standard curve (copy number as a function of Ct) was created by a 10 mass dilution series of each cDNA fragment

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Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

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Two of the most commonly characterized genes in this regard are the serotonin transporter (SLC6A4) and FK506 binding protein 5 (FKBP5) (Olson et al., 2011) and decreased secretion of 5-hydroxytryptamine (5-HT) hormones (Rauch et al., 2006