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The gut microbiota profoundly influences the cytotoxicity of tumor-infiltrating CD8+ T cells and impacts the clinical efficacy of immune checkpoint therapies [78]

muciniphila , the species that decreased in old mice, improved the intestinal senescence-related phenotype, and extended the healthspan ( gerobiotics '' is defined for the probiotic strains and their derived postbiotics and para-probiotics able to beneficially attenuate the fundamental mechanisms of aging, reduce physiological aging processes, and thereby expand the host health span (Tsai et al., 2021)

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