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Since some db/db mice succumbed to this treatment probably due to RIF toxicity at 16 mg/kg, we reduced the dose to 8 mg/kg and treated the animals 3 times weekly through oral gavage from day-4 onwards until 8 weeks post-infection

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Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]

Any reference to biological activity or potential effects is based solely on preclinical or in vitro findings and should not be interpreted as validated clinical outcomes