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Beyond sleep, researchers have studied DSIP for its effects on stress hormone regulation specifically its ability to modulate ACTH and cortisol secretion making it of interest in HPA axis research

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Such an indication is unique from most other drugs and compounds identified by the NIA-supported Intervention Testing Program (ITP) to improve lifespan, as acarbose, 17--estradiol, nondihydroguaiaretic acid (NDGA), and protandim, all preferentially improve male lifespan 35,36