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These peptides represent a novel class of therapeutic agents that may offer alternatives to traditional treatment approaches for various pathological conditions

It not only stabilizes Nrf2, but it also activates a number of cytoprotective genes (HO-1, NQO1, GCLC/GCLM, and other phase-II enzymes) that protect cells from lipid peroxides, restore glutathione balance, and keep mitochondria healthy

(82) developed a mouse MI model and, through transcriptomics and network analysis, uncovered alterations in metabolic pathways during MI, providing new perspectives for tissue-specific therapeutic targets

All studies were conducted strictly in accordance with the approved research protocol after obtaining written informed consent from the subjects

Moy SS, Teng BL, Nikolova VD, Riddick NV, Simpson CD, Van Deusen A, et al