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[86] discovered that suramin influenced the expression of numerous genes implicated in the function of the mitochondrial respiratory chain complexes I and IV [86]

Methylglyoxal (MG) is a highly reactive and toxic side-product of glucose, lipid and protein metabolism, with glycolysis being its major source 37,47,48

Secondary progressive and relapsingremitting Multiple Sclerosis were differentiated by perturbed tryptophan and pyrimidine metabolism with altered kynurenate, 5-hydroxytryptophan, 5-hydroxyindoleacetate, N-acetylserotonin, uridine, deoxyuridine, thymine and glutamine 65

Dinkova-Kostova AT, Kostov RV, Kazantsev AG

26 An article that is often cited in support of differential therapeutic claims for iodine and iodide, reported three studies of women with fibrocystic breast disease