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[DOI] [PMC free article] [PubMed] [Google Scholar] 168.Yucra S., Gasco M., Rubio J., Nieto J., Gonzales G.F

J Orthop Sports Phys Ther Blog

In any scenario, personalized treatment strategies and meticulous monitoring are indispensable to ensure the best possible therapeutic outcomes

Development 125, 11911205

Subsequent work by Sun and colleagues in the APP/PS1 mouse model identified downstream PI3K/AKT pathway activation as a major component of the mechanism, with the PI3K inhibitor wortmannin reversing Dihexas anti-inflammatory and anti-apoptotic effects [5]