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Notably, nutrient deprivation-induced ERS also influences the tumor immune microenvironment, transmitting regulatory signals via exosomes and other carriers to suppress T-cell function and promote the polarization of immunosuppressive M2-type macrophages [24]

These people are suffering from a breakdown in the immune system called toxicant-induced loss of tolerance, or TILT

Lin X, Zhan B, Wen S, Li Z, Huang H, Feng J

Hypertension 81 , e41e43 (2024)

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