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Additionally, probiotics exhibit insufficient colonization capacity on gastrointestinal mucosal surfaces, which is further influenced by host microbiota composition and intestinal transit rate

Protective effect of Pentadecapeptide BPC 157 against experimental colitis involves neuropeptides neurokinin1 receptor/substance P system activation: role for mast cells degranulation inhibition via mitogenactivated protein kinases pathways modulation Cell Signal 27(5): 9961007 Kiefer JW Jr., Lee CLF

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While tamoxifen is highly effective in the management and prevention of breast cancer, yet, it may provoke adverse reactions including hot flushes, vaginal bleeding, endometrial polyps, and hyperplasia, and less common endometrial tumor, pulmonary embolism, stroke, porphyria, and liver injury 9,10,11,12