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The modulation of PI3K/AKT/PKB, NF-B, MAPK, and other signaling pathways, as well as the production of associated cytokines and protein kinases involved in controlling cell apoptosis and proliferation, are all part of the mechanisms of action (53, 54)

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65 The ability of GSH administration to prevent nephrotoxicity from renal ischemia, and consequent production of oxygen free radicals, has been investigated

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