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doi: 10.3389/fgene.2022.1060529 Received 03 October 2022 Accepted 14 November 2022 Published 28 November 2022 Volume 13 - 2022 Edited by Turgay Unver, FicusBio, Turkey Reviewed by Jianzhao Li, Ludong University, China Yong-Fang Li, Henan Normal University, China Updates Copyright 2022 Li, Li, Sun, Wang, Ren, Liu and Gao

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Lees et al., 2008)

The preparation of freeze-dried powder is divided into two types in the existing freeze-drying process, wherein the first type is to freeze-dry raw materials, crush and screen the raw materials under the aseptic operation condition and fill the powder, although the freeze-drying cost is low, the reduced glutathione powder for injection prepared by the method is easy to absorb moisture, decompose and deteriorate, the medication safety is influenced, and the insufficient filling amount is easy to cause

For example, -KG acts as a cofactor for the activation of the histone demethylase JMJ family (Jumonji) to promote histone demethylation (102, 125)