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The typical integrative or functional medicine practice sees patients with a variety of chronic illnesses including, but not limited to, autoimmunity, heart disease, diabetes, COPD, neurodegenerative states, and the gray area of undiagnosed unexplained nonspecific inflammation as evidenced by lab evaluations and physical presentation

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While GHSR1a activity in the hypothalamus is likely heavily involved in homeostatic mechanisms, its presence in extra hypothalamic regions, including a number of limbic and midbrain structures like the ventral tegmental area (VTA), suggest that this receptor is associated in processes associated with learning and motivation (Abizaid et al., 2006