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In the LPS-induced inflammatory model, butyrate supplementation improved gut morphology and reduced inflammation, evidenced by increased villus height and villus height-to-crypt depth ratio, while lowering inflammatory markers such as NF-B and IL-1, thereby contributing to intestinal integrity

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We also refer readers to the CY 2017 Quality Payment Program final rule (81 FR 77199 through 77245), CY 2018 Quality Payment Program final rule (82 FR 53663 through 53688), CY 2019, CY 2021, CY 2022, CY 2023, and CY 2024 PFS final rules (83 FR 59785 through 59820, 84 FR 62991 through 63006, 85 FR 84886 through 84895, 86 FR 65466 through 65490, 87 FR 70060 through 70087, and 88 FR 79351 through 79365, respectively) for a description of previously established policies related to the Promoting Interoperability performance category