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Oxidative damage also results in the accumulation of cellular metabolic byproducts like lipofuscin within the RPE cells, further exacerbating cellular dysfunction and death by disrupting autophagy and affecting normal metabolism (222, 225)

Sreerag NK, Kashyap P, Shilpa VS, Thakur M, Goksen G (2025) Recent advances on mycelium based biocomposites: synthesis, strains, lignocellulosic substrates, production parameters

GHRH stimulation of pituitary cell cultures in the presence of a specific ghrelin receptor inhibitor significantly decreased the GH response to GHRH challenge, although this effect was not observed in the absence of GHRH stimulation