Nature 423: 456461 Hsu YT, Youle RJ (1998) Bax in murine thymus is a soluble monomeric protein that displays differential detergentinduced conformations
In one embodiment the present invention relates to a vaccine composition comprising one or more pharmamers, wherein the one or more pharmamers has a molecular weight in the range 50,000 Da to 5,000,000 Da, such as from 50,000 Da to 100,000 Da, for example from 100,000 Da to 200,000 Da, such as from 200,000 Da to 300,000 Da, for example from 300,000 Da to 400,000 Da, such as from 400,000 Da to 500,000 Da, for example from 500,000 Da to 600,000 Da, such as from 600,000 Da to 700,000 Da, for example from 700,000 Da to 800,000 Da, such as from 800,000 Da to 900,000 Da, for example from 900,000 Da to 1 ,000,000 Da, such as from 1 ,000,000 Da to 1 ,200,000 Da, for example from 1 ,200,000 Da to 1 ,400,000 Da, such as from 1 ,400,000 Da to 1 ,600,000 Da, for example from 1 ,600,000 Da to 1 ,800,000 Da, such as from 1 ,800,000 Da to 2,000,000 Da, for example from 2,000,000 Da to 2,200,000 Da, such as from 2,200,000 Da to 2,400,000 Da, for example from 2,400,000 Da to 2,600,000 Da, such as from 2,600,000 Da to 2,800,000 Da, for example from 2,800,000 Da to 3,000,000 Da, such as from 3,000,000 Da to 3,200,000 Da, for example from 3,200,000 Da to 3,400,000 Da, such as from 3,400,000 Da to 3,600,000 Da, for example from 3,600,000 Da to 3,800,000 Da, such as from 3,800,000 Da to 4,000,000 Da, for example from 4,000,000 Da to 4,200,000 Da, such as from 4,200,000 Da to 4,400,000 Da, for example from 4,400,000 Da to 4,600,000 Da, such as from 4,600,000 Da to 4,800,000 Da, for example from 4,800,000 Da to 5,000,000 Da
Indeed, in a systematic review with meta-analysis, Giugliano et al
Effects of sevelamer hydrochloride and calcium acetate on the oral bioavailability of ciprofloxacin
10.3390/ijerph191911980 4
