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In addition, these studies show the lack of extracellular GSH and SCN may sensitize CFTR deficient cells to HOCl mediated toxicity

PPAR, Peroxisome proliferator activated receptor

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Disclosures: Dylan Windell: Perspectum: Employee, asd: Employee, Alastair Magness: Nothing to Disclose, Abhishek Roy: Nothing to Disclose, Paul Aljabar: Nothing to Disclose, Timothy Kendall: Nothing to Disclose, Eve Fryer: Nothing to Disclose, Kenneth Fleming: Nothing to Disclose, Rob Goldin: Nothing to Disclose, Caitlin Langford: Nothing to Disclose 776 THE USE OF AI-ASSISTED DIGITAL PATHOLOGY IN DETERMINING THE INFLAMMATORY BURDEN IN LIVER DISEASE Dylan Windell 1 Cayden Beyer 1 Sarah Larkin 1 Elizabeth Shumbayawonda 1 Paul Aljabar 1 Caitlin Langford 1 Andrea Dennis 1 Rob Goldin 2 , 1 Perspectum, 2 Imperial College London Background: Liver pathology assessment remains the reference standard for assessing disease activity despite well reported limitations, notably the high variability between readers especially in the assessment of inflammation

Stronger oxidative stress is caused by H