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CagriSema (cag + sema) is the closest analog with human trial data

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Deboever N, Mitchell KG, Nelson D, Farooqi A, Ludmir EB, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Heymach JV, Gomez DR, Gandhi SJ, Antonoff MB

Haem oxygenase-1 induction reverses the actions of interleukin-1 on hypoxia-inducible transcription factors and human chondrocyte metabolism in hypoxia

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