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Ackowledgements The authors acknowledge the financial support of the Innovation and Science Ministry (PN/PETRI/PR/2007-019) and the Ministry of Economics and Competitiveness (PI16/00784)

buffer 2: 20 mM HEPES, pH 7.5, 100 mM NaCl, 0.02% DDM, 0.02% CHS, 0.07% MNG

Consistent with our previous study 15 , the injection of fentanyl was associated with minor increases in BT that would have minimal direct effects on breathing

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Once the surgical modifications are finished, a nasal splint will be placed to support your nose during the first week of recovery and healing