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The signal transducer and activator of transcription 3 (STAT3) protein is a transcription factor known to stimulate immunosuppressive cells, e.g., myeloid-derived suppressor cells (MDSC) and regulatory T cells (Treg), activated in chronic inflammatory conditions [8, 9]

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Within specific genomic regions and throughout the genome, changes in DNA methylation and hydroxymethylation can be seen following sleep deprivation

Our data showed that QCHS enriched pathways involved in arachidonic acid metabolism, biosynthesis of unsaturated fatty acids, and linoleic acid metabolism