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Zhang C, Xu T, Zhang D, He W, Wang S, Jiang T

Statins can cause adverse side-effects, including musculoskeletal complaints, known as myositis, fatigue, gastro-intes- tinal discomfort, elevation of liver enzymes, neurocognitive symptoms, peripheral neuropathy and insomnia

Tumor-derived EV metabolites, such as succinate and glycolytic enzymes, influence metabolic reprogramming and the tumor microenvironment, but mechanistic data linking EV-mediated metabolic transfer to inflammation-driven colorectal carcinogenesis are still developing (Haque et al., 2025