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Alternative medicine [edit] With the growth of direct-to-consumer genetic testing, the alternative medicine industry has aggressively targeted a range of dubious tests [43] and highly profitable quack treatments for claimed MTHFR polymorphisms, despite the lack of any demonstrated health effects of these mutations

doi: 10.1016/j.fertnstert.2008.05.016

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It was finally approved by NICE for treating severe persistent allergic asthma last year, after previously being rejected in draft guidance because of question marks over its cost-effectiveness

A p-value less than 0.05 was considered statistically significant