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However, combination protocols remain unstudied and purely theoretical

These infections are widespread in the developing countries, especially in the tropical and subtropical countries like India, where the temperature of the environment and relative humidity are high

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Level A Anchor Evidence: Unlike the SCFAsmodule, the Bile Acid/Tryptophan module (and broader comprehensive metabolic reprogramming) lacks Level A closed-loop anchors that converge the causal chain to specific bile acid or indole metabolite molecules

250 Therefore, targeting dyslipidemia and its downstream effects may offer promising therapeutic avenues for DPN management (Fig